The European Research Infrastructure for the generation, phenotyping, archiving and distribution of mouse disease models (INFRAFRONTIER) aims to build a distributed world-class Research Infrastructure that provides the biomedical research community with the tools needed to unravel the role of gene function in human health and disease. By offering access to a unique collection of mouse models and research tools and associated data, and to state-of-the-art technologies for mouse model development and phenotype analyses, INFRAFRONTIER enhances medical research and promotes studies that lead to breakthrough discoveries in cancer, metabolic and cardiovascular diseases, lung diseases, infectious diseases and the group of rare diseases, global threats to our socio-economic well-being.

INFRAFRONTIER entered the ESFRI Roadmap in 2006 and established a Company with Limited Liability under German law (GmbH) in 2013, based on a MoU signed by six members, research organisations mandated by their national research ministries, and including EMBL. The INFRAFRONTIER GmbH provides central access to all the services of the INFRAFRONTIER Research Infrastructure via its website. It improves access for the users, both from academia and industry, by building capacities for systemic phenotyping, archiving and distribution of mouse models and by providing an efficient and transparent access process, based on peer-evaluated scientific excellence. The INFRAFRONTIER Research Infrastructure currently brings together 23 scientific partners from 15 European countries and Canada.