The Integrated Structural Biology Infrastructure (INSTRUCT) is a distributed Research Infrastructure that provides peer-reviewed access to a broad palette of high-end technologies and methods, expertise and training in structural biology. INSTRUCT major goal is underpinning fundamental research and promoting innovation in the biological and medical sciences by providing an integrated approach that combines multiple technologies. INSTRUCT is a major player in delivering this strategy by creating close cooperation with other biological and medical sciences Research Infrastructures and establishing international partnership both with academia and industry supporting the biotechnology and pharmaceutical industries, and helping to tackle the Grand Challenges as defined by Horizon Europe.

Entered the ESFRI Roadmap in 2006, INSTRUCT established the European Research Infrastructure Consortium (ERIC) in 2017. INSTRUCT ERIC consists of 15 Members, including EMBL, and one Observer and provides access to cutting-edge technology and scientific expertise in structural biology by means of 11 INSTRUCT Centres. Each Centre has contributed a range of instruments to the catalogue of platforms for a total of 26 facilities delivering 78 services. The INSTRUCT Hub acts as the point of contact and administrative centre for all organizational and reporting activities to the consortium and the community. Through international collaborative projects, INSTRUCT ERIC has been able to offer these services to users from outside Europe, outlining the advantages at trans-continental level.